DR. PRADEEPKUMAR CHANDANE

DR. ASHWINI KORANNE, DR. SHREYA SHAH, DR. MEHUL SHAH

Abstract

INTRODUCTION:MARFAN SYNDROME (MFS) IS A GENETIC DISORDER ASSOCIATED WITH CONSIDERABLE MORBIDITY AND MORTALITY. PRESENTLY, WELL-DOCUMENTED INFORMATION IS NOT AVAILABLE IN INDIA.

METHODS IN RETROSPECTIVE COHORT STUDY,WE RECRUITED PATIENTS WITH CLINICALLY DIAGNOSED MFS USING REVISED GHENT NOSOLOGY. COMPLETE OPHTHALMIC INFORMATION EXPORTED FROM EMR, SURGICAL DETAILS AND FOLLOW-UP DATA WERE OBTAINED IN A SPECIFIC, PRE-TESTED FORMAT.

RESULT:OUR COHORT CONSISTED OF 86 EYES OF 43 PATIENTS. PREVALENCE 20.5 PER 100,000 INDIVIDUALS. MEAN AGE OF THE PATIENTS WAS 23.9 YEARS. ALL EYES WERE TREATED EITHER OPTICALLY WITH REFRACTION OR SURGICALLY USING LENSECTOMY AND VITRECTOMY WITH SUTURE SUPPORTED SCLERAL FIXATED INTRAOCULAR LENS (IOL), WHICH MADE A SIGNIFICANT DIFFERENCE IN THE VISUAL OUTCOME (P = 0.00).

CONCLUSION:ALTHOUGH CONSIDERED A RARE DISEASE, MFS IS COMMONLY FOUND IN THE OPHTHALMOLOGICAL SETTING. REFRACTION AND SURGERY(LENSECTOMY WITH SFIOL) IMPROVES VISION.