DR. VANITA PATHAK RAY

Abstract

Purpose: To investigate the comparative efficacy and safety of topical trabeculectomy with a standard dose of injected Mitomycin C (MMC) with or without Ologen®(O) Methods: Retrospective review of consecutive patients >18 years who underwent injected MMC (0.05 ml of 0.04% solution) with trabeculectomy with or without Ologen®, under topical anaesthesia. Primary outcome measure was IOP and secondary were BCVA, number of antiglaucoma medications(AGMs), complications. Results: 24 eyes underwent Trab+InjMMC+O with follow-up of 10.3±5.4 months, and 25 eyes underwent Trab+InjMMC alone followed for 28.0±16.3 months. Mean preoperative IOP, AGM, and BCVA did not differ between the groups. Post-operatively IOP (p=0.035) was significantly reduced in the Trab+MMC+O group along with rate of complications (p=.045)and interventions (p=.05) but AGM and BCVA did not differ. Conclusions: Both procedures are efficacious in lowering IOP but use of Ologen makes it significantly more efficacious, and safe.