DR. SHANTANU GULATI
Dr. M.N. MANGALA, DR. SOUMYA H.V., DR. ANITA T. GIRISH, DR. PRABHAKAR S.K.
Abstract
Purpose: To report cases of angle closure crises precipitated by systemic medication.
Materials and Methods : Case Series
Case 1: A businessman on Topiramate therapy for migraine presenting with blurring of vision and episodes of vomiting.
Case 2: A homemaker on Losartan therapy for hypertension presenting with ocular pain, blurring, redness and watering.
Case 3: A farmer on Ciprofloxacin and Paracetamol therapy for prick wound, presenting with vomiting, ocular pain, and redness (possibly first reported).
All patients underwent Slit lamp examination, Intra Ocular Pressure, Anterior segment OCT and B scan confirming angle closure attack.
Result: In all cases the suspected offending drugs were withdrawn and managed medically with the goal of reducing IOP and inflammation.
Conclusion: Drug induced angle closure attack is a relatively uncommon ophthalmic emergency and a diagnosis of exclusion. Clinicians should have a high index of suspicion in angle closure attacks without obvious cause


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