DR. MANPREET KAUR

Abstract

Neurofibromatosis (NF) is a genetic disorder that affects the cell growth of neural tissue, leading to tumor growths that involve the skin, nervous system, eyes and other organs. In 1987, the National Institute of Health Consensus Development Conference on Neurofibromatosis reclassified the disorder into two primary subgroups: Neurofibromatosis type 1 (NF1) and Neurofibromatosis type 2(NF2). An individual with at least two of the following criteria is considered affected by NF1:

at least six café au lait spots,inguinal and/or axillary freckling, at least two Lisch nodules, optic pathway glioma, typical bony lesions such as sphenoid wing dysplasia, pseudoarthrosis of the tibia and a first-degree relative with NF. Neurofibromas are tumors that arise from peripheral nerve sheaths and contain a variety of cell types.

The author here describes a case of NF1 with plexiform neurofibroma of lower eyelid.