DR. ISHA AGARWAL

DR.RAHUL MAYOR

Abstract

22 year old male presented with blurring of vision in both eyes. Visual acuity was 6/24 N18 in the right eye and 6/6p N6 in the left eye. Anterior segment was unremarkable. Fundus examination revealed active occlusive retinal vasculitis in both eyes with exudates over macula in right eye and a thick ERM in the left eye. Ancillary investigations- FFA and OCT were done. Baseline uveitis work up was within normal limits. High titres of IgM & IgA autoantibodies against Beta2GPI and Anti-cardiolipin antibody IgM were detected which was suggestive of Antipospholipid Syndrome (APA). Patient was co-managed along with a rheumatologist. APS is more common in women than men, clinician should have a high index of suspicion when a young to middle aged adult presents with bilateral occlusive vasculitis. Ocular findings are seen in 15-88% of patients with primary APS. Early diagnosis and treatment may prevent site threatening & life threatening complications of APS.