DR. ARCHANA SINHA

Dr. SUNIL KUMAR, DR. AANCHAL PRIYA, DR. ANUPAMA SHARMA

Abstract

Purpose: To compare the effects of Intravitreal injections of Bevacizumab and Triamcinolone for the treatment of CME in non-infectious uveitis.

Methods: 40 eyes of 35 consecutive patients with CME associated with non-infectious uveitis were randomized to 2 groups. 20 eyes were treated with 1.25mg of IVB and 20 eyes received 4mg of IVT. The clinical course of BCVA, IOP and CMT by optical OCT was monitored for up to 6 months after the initial injection.

Results: The best visual acuities were achieved 1 month after injection in both groups. In IVB group improvement in VA was achieved in 16/20(80%) of eyes and in IVT group was 19/20(95%). In IVT group IOP was found to be raised. The CMT reduction in the IVT group was from 298.52µ to 197.68µ and in IVB group was from 311.76µ to 227.13µ.

Conclusion: Both IVB and IVT treatments can effectively improve BCVA and reduce CMT in uveitic CME patients. The CMT reduction was greater in IVT group than IVB group. The IVT group causes increase in IOP.

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