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  5. FP1302 : Scheimpflug analysis of Corneal haze following different CXL techniques for keratoconus

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Dr. Barkha Gupta

Dr. CHINTAN SINGH (MALHOTRA), Dr. ARUN KUMAR JAIN, Dr.Supriya Dhar

Abstract

A retrospective study evaluated corneal haze & compared its course in different CXL techniques for keratoconus- standard epithelium off CXL (47 eyes), contact lens assisted (CACXL- 30 eyes), and transepithelial (TECXL 7 eyes) using Scheimpflug tomography.

The baseline mean density score of central anterior layer was 16.14, 15.85, and 15.89 in standard CXL, CACXL, and TECXL groups respectively (p 0.93). After standard CXL, the score increased to 31.34 at 3months (p<0.001) and decreased to 23.72 at 12months (p 0.003). Post-CACXL, it peaked at 3months (20.35, p 0.14) and returned towards baseline at 6months (18.82, p 0.15). After TECXL, it increased slightly at 1month (18.47, p 0.17), decreased at 3months, and plateaued over 1year. A similar amount of flattening was noted with all 3 procedures at 12 months (p 0.64). Significant haze was seen after standard CXL than CACXL &amp; TECXL. No correlation with topographic change was noted. The extent of haze may not be predictive of CXL efficacy.

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