DR.RICHA KAMAL

DR. PARTHA BISWAS, DR. ANINDYA KISHORE MAJUMDER, DR. DIVYA J

Abstract

A 41 years female presented with double vision,headache and discomfort in botheyes,following generalized weakness,walking difficulty and loss of taste for past 2months.She had diplopia more in right gaze with grade1vitritis and snowballs in righteye(RE).She was investigated and neurologist opinion taken that showed ANA(Hep-2),Anti-NMDA-R,Anti-RO and Anti-Centromere antibody positive,lower limbs veno-occlusive disease in Doppler study ,diagnosed as CLIPPERS disease and received pulse methyl prednisolone.We did RE posteriorsubtenon injection and fluorescein angiography guided sectoral LASER photocoagulation,for leaking vascular proliferation.She improved over 2weeks time and is under close followup.

CLIPPERS Disease is a rare CNS inflammatory disorder involving predominantly Pons with retinal Vasculitis,uveitis and diplopia(most commonly reported)mentioned in literature.Here we probably report for the first time retinal vasculitis as a presenting sign of CLIPPERS Disease,from India.