Dr. SANKHA SUBHRA CHAUDHURI

DR. MOUSUMI BANERJEE, DR. MADHURIMA CHAUDHURI

Abstract

Introduction:An imbalance in the systemic redox status leading to oxidative stress has been an important factor in development of senile cataracts, which is reflected by an increase in serum TBARS and a decrease in plasma SOD activity. AIM:In the present study the role of serum zinc level and plasma SOD activity was analyzed in senile cataract patients showing significant oxidative stress. Results: Serum TBARS, plasma SOD and serum zinc level was measured in 30 randomly selected cataract patients against properly matched controls. The analysis of means showed a significant increase in serum TBARS and decrease in plasma SOD and serum zinc level in cases, but plasma SOD was found to be just significantly correlated (p = 0.05) with the serum zinc only in the cases. The results of partial correlation studies and multiple regression analysis, also, showed only a significant correlation and predictable dependence between serum TBARS and plasma SOD, excluding the role of serum zinc.