DR. DIVYA KESARWANI

DR. VAIBHAV KUMAR JAIN, DR. KUMUDINI SHARMA, DR. VIKAS KANAUJIA

Abstract

Purpose: To evaluate the corneal biomechanical properties in patients with connective tissue disorders (CTD), and compare them with age-matched healthy control. Methods: In this prospective study, 62 patients (study group) with CTDs and 44 healthy subjects (control) underwent Ocular Response Analyzer and corneal pachymetry measurements. Right eye of a subject was assessed for corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPcc), and Goldmann-correlated intraocular pressure (IOPg), and central corneal thickness (CCT). Results: Mean CH [9.54±1.66 mm Hg (study group) and 10.62±1.21 mm Hg (control); P=0.013) and mean CRF [9.95±1.47 mm Hg (study group) and 10.76±1.25 mm Hg (control); P=0.040] were significantly different between groups. Mean IOPcc, IOPg, and CCT were not significantly different between groups. Conclusion: CH and CRF are altered in CTDs which may underestimate IOP so these should be considered in patients with CTDs.