DR. ESHA SHAH

DR.DR. NUTAN BEDI, DR. ARCHANA GULATI

Abstract

Introduction: A myriad of ocular manifestations in acute lymphoblastic leukemia (ALL) are due to leukemic infiltration or as a result of anemia, thrombocytopenia and leukocytosis. Method: 5 patients of ALL were evaluated. Detailed slit lamp anterior segment examination and posterior segment evaluation using indirect ophthalmoscopy was done. Results: It is bewildering to note that each patient of ALL that we examined presented with different ocular manifestations. They varied from retinal haemorrhages, subhyaloid haemorrhage, papilloedema, optic atrophy and proptosis. In 2 patients ophthalmic signs preceded the systemic manifestations and thus led to the diagnosis of ALL after CBC with PBF and bone marrow aspiration. Prompt chemotherapy as per protocol with supportive treatment was started. Conclusion: Early recognition of leukemic retinopathy and any questionable ocular finding must be followed up with a detailed systemic evaluation which would help in darting the targeted disease.