DR. KUSUM CHAUDHARY

DR.(MISS) MITALI BOROOAH

Abstract

OBJECTIVES: To determine association between serum Vitamin D levels and severity of diabetic retinopathy. METHODS: 130 type 2 DM patients (>18yrs) attending ophthalmology department of tertiary care hospital between july 2019 to june 2020 were assessed. Patients were tested for FBS, PPBS, HbA1c, serum creatinine and 25- hydroxy-vitamin D. Vitamin D levels were determined by chemiluminescent immunoassay method. Patients were classified into 3 groups based on funduscopic findings: No diabetic retinopathy(No DR), Non-proliferative(NPDR) and Proliferative diabetic retinopathy(PDR). RESULTS: Proportion of patients with vitamin D insufficiency(<30ng/ml) were higher in PDR group(100%) as compared to NPDR(71.7%) and No DR(64.29%). Mean vit D levels were significantly lower in patients with longer duration of DM, higher HbA1c levels and those on insulin treatment. CONCLUSION: Patients with higher grades of retinopathy had lower vitamin D levels and were more likely to be vitamin D insufficient.