DR. POONAM SINGH

Dr. VIJAYA JOJO, Dr. SUSHIL BAJORIA, Dr. BHARTI SHARMA

Abstract

Aims: To compare the prevalence and severity pattern of OSD in patients using antiglaucoma medications vs normal subjects Materials and Methods: 103 patients with antiglaucoma drops were included in the study group. Age- and gender-matched normal subjects (n = 103) as control group. They were assessed for OSD using (OSDI) questionnaire, TBUT, Lissamine green staining, and Schirmer’s test. Results:The prevalence of OSD was significantly more in the study group when assessed by FTBUT (83.5%) vs Normal (57.3%) with P < 0.001, with Schirmer I (30.1% vs. 17.5%); P = 0.033, and with ocular surface staining (62.1% vs. 31.1%); P < 0.001. Antiglaucoma medications also had worse grades of OSD evaluated by FTBUT (P = 0.001), Schirmer I (P = 0.023), and ocular surface staining (P < 0.001).Conclusions: OSD was more common in patients using intraocular pressure (IOP)-lowering drugs than in controls. Long-term therapy and multiple medications were associated with severe OSD