DR. PRANAY KUMAR

DR.ALKA JHA, DR.MANOJ KUMAR

Abstract

Purpose:-Diabetic retinopathy is a leading cause of blindness in adults and is unique in displaying a uniform epidemiological profile world wide.The objective of the study is to determine the strength of association between Lipid profile and the severity of diabetic retinopathy.Methods:-The study comprised a total of 200 Diabetic patients(100 with Diabetic retinopathy and 100 without diabetic retinopathy) and 100 age and sex matched Non -Diabetic patients(control group).Ophthalmoscopic and biomicroscopic examination of ocular fundus was done.Serum lipid profile and blood sugar estimation were done by enzymatic method.Results:- There was a significant association between serum cholesterol level and Diabetic retinopathy(p= 0.016).Hypercholesterolemia was found to be significantly associated with severe NPDR,very severe NPDR,PDR and CSME.Conclusions:-Hypercholesterolemia appears to be a risk factor for diabetic retinopathy and clinically significant macular edema.