DR. ARVIND KUMAR

DR. VIRESHWAR PRASAD, DR.ALKA JHA, DR. ABHAY RANJAN SINGH

Abstract

AIM: To evaluate the efficacy of intrastromal injection of voriconazole in resistant cases of funal corneal ulcer

METHOD: During period 2019 to 2021, 30 cases of fungal corneal ulcer were diagnosed on the basis of clinical findings and KOH staining. They were treated with topical natamycin (5%) and voriconazole(1%). 10 cases who did not improved judged clinically by increasing size of the ulcer and clinical sign. They were subjected to intrastromal voriconazole(50mcg/0.1ml) around ulcer in 4 meridians.

RESULT: 6 cases improved clinically and rest 4 cases which did not improved were referred for therapeutic keratoplasty.

CONCLUSION: In resistant cases of fungal corneal ulcer intrastromal voriconazole injection can be used.