DR.PRIYANKA MANDRAHA
Dr.PROF. PANKAJ CHOUDHARY
Abstract
To evaluate RNFL & GCL thickness in patients with optic neuritis
Method: 25 eyes of 25 patients with optic neuritis(unilateral involvement) in age group18-65 yrs were include in 1 year of period. Based on disc changes, average RNFL & GCL thickness were measured by SD-OCT in patients with optic neuritis & compared with control of same age group.
Result: Mean± SD value of average RNFL thickness in optic neuritis was 226.5±91.90 and control eyes was 91.89±12.64µm (p<0.0001)& average GCL thickness mean± SD in optic neuritis were 64.57±24.35 and control eyes were 82.58±8.21µm(p<0.0001) respectively. Conclusion: Quantification of RNFL & GCL thickness by OCT provides indirect measure of axonal & neuronal loss in anterior visual pathways.GCC loss is hallmark of optic neuropathy & should be monitored for early detection & prognosis in optic neuritis.
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