Dr. Gairik Kundu

DR. SAILIE SHIRODKAR, Dr. ROHIT SHETTY, Dr. POOJA KHAMAR

Abstract

Purpose – To assess collagen distribution in normal and suspicious eyes with polarisation sensitive OCT (PS-OCT)

Methods – 50 healthy and 35 suspicious eyes were imaged using ultrahigh resolution PS-OCT. Phase Retardation (PR) enface maps from the posterior surface were generated. Zonal analysis was performed on the enface maps in annular zones from center to periphery.

Results – PR maps of normal eyes showed preferential arrangement of collagen fibrils, with least retardation in apex (21⁰) and increasing gradually towards periphery (47⁰). Suspect corneas showed visibly different arrangement. Zonal analysis showed higher PR in suspects compared to normal eyes, which was statistically significant. (p<0.05) Conclusion – PS-OCT identified differences in collagen distribution in normal and suspicious corneas, possibly indicating weaker biomechanics. PS-OCT can be used in clinical settings for early diagnosis of KC in normal/suspicious topography and screening for refractive procedures.

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