DR. PARTH MEHTA

DR. CHETAN RAO

Abstract

Aim: To study the clinical features and microbiological profile of panophthalmitis cases managed in a tertiary care centre.

Methods: Retrospective case study of microbiological analysis of clinically diagnosed panophthalmitis in a 10 year period.

Results: Out of 107 cases, Exogenous were 79(commonest cause: trauma) and endogenous: 28. Amongst culture positive cases (n=79), Pseudomonas was most common bacteria (19), Aspergillus was the most common fungi (5). Gram positive isolates showed 92.7% sensitivity to Vancomycin, gram negatives showed 83% sensitivity to Amikacin and 48% resistance to Ceftazidime. Combination of T- sign (ultrasound), restriction of extraocular movements and no perception of light showed positive predictive rate of 95% of need of evisceration. Globe was salvageable in 13 cases.

Conclusion: Globe rescue is poor in panophthalmitis. Vancomycin for gram positives and Amikacin for gram negatives is recommended as the first-choice antibiotics to attempt globe salvage.