DR. LISA PATEL

DR. KRISHNA SHAH, DR. VAISHALIBEN PRAJAPATI, DR. DEEPIKA SINGHAL

Abstract

PURPOSE: Pseudoexfoliation Syndrome (PEX) is characterised by the production and accumulation of extracellular granular fibrillar material in many ocular tissues. Studies report that in patients with PEX,corneal endothelium shows different features like reduced cell density(800-1500 cell/mm2),higher variation in cell size and lower percentage of hexagonal cells.This study aims to evaluate the influence of PEX on the cornea, and determine the potential use of quantifiable corneal characteristics as clinical biomarkers to risk stratify patients with PEX.

METHODS:100 patients diagnosed with PEX on slitlamp biomicroscopy are enrolled in this study,have undergone complete eye examination.

RESULTS:In enrolled participants results revealed that CCT in PEX eyes is significantly thinner compared to normal eyes.

CONCLUSION:The study confirms the existence of significant difference in various corneal morphometric parameters in PEX patients and its association in development of secondary glaucoma.