DR. SAMRUDDHI DALAL

DR. ARAVIND ROY

Abstract

Retrospective case report. A 50 year-old female, presented with RE 360 degree peripheral corneal thinning along with overhanging edges. Diagnosis of RE Peripheral ulcerative keratitis was made. A systemic association was suspected and was found to be c-ANCA positive and after rheumatology opinion diagnosed as having Granulomatosis with Polyangitis along with involvement of other systems. Patient was non-compliant for systemic medications and hence worsened, leading to increased RE peripheral corneal thinning along with adjacent scleral thinning for which RE scleral patch graft was done. Following which her RE was tectonically stable.CONCLUSION:. Ocular manifestations such as peripheral ulcerative keratitis in the setting of scleral inflammation can present as the initial signs of GPA. These features should alert the doctor/optometrist and prompt a thorough diagnostic approach and an aggressive treatment given that it could reveal a life-threatening disease.